Martin Perreault Selected Research

Mestranol

2/2020	Minor chemical modifications of the aminosteroid derivative RM-581 lead to major impact on its anticancer activity, metabolic stability and aqueous solubility.
1/2018	Parallel Solid-Phase Synthesis using a New Diethylsilylacetylenic Linker and Leading to Mestranol Derivatives with Potent Antiproliferative Activities on Multiple Cancer Cell Lines.
1/2017	Design of a Mestranol 2-N-Piperazino-Substituted Derivative Showing Potent and Selective in vitro and in vivo Activities in MCF-7 Breast Cancer Models.

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Martin Perreault Research Topics

Disease

6	Neoplasms (Cancer) 10/2021 - 11/2016
5	Prostatic Neoplasms (Prostate Cancer) 10/2021 - 02/2010
2	Pancreatic Neoplasms (Pancreatic Cancer) 02/2020 - 01/2019
2	Breast Neoplasms (Breast Cancer) 01/2017 - 01/2016
1	Liver Diseases (Liver Disease) 07/2021
1	Ovarian Neoplasms (Ovarian Cancer) 01/2018
1	Cholestasis 01/2010
1	Sclerosing Cholangitis 01/2010

Drug/Important Bio-Agent (IBA)

5	RM-581IBA 10/2021 - 01/2017
4	AndrogensIBA 10/2021 - 02/2010
3	Mestranol FDA Link 02/2020 - 01/2017
2	Antineoplastic Agents (Antineoplastics)IBA 10/2021 - 01/2021
2	Pharmaceutical PreparationsIBA 07/2021 - 11/2016
2	androstaneIBA 01/2019 - 01/2017
1	Docetaxel (Taxotere)FDA Link 10/2021
1	Ursodeoxycholic Acid (Urso)FDA LinkGeneric 07/2021
1	Biological ProductsIBA 01/2021
1	Phosphates (Orthophosphate)IBA 02/2020
1	sulfamic acid (ammonium sulfamate)IBA 02/2020
1	Acetates (Acetic Acid Esters)FDA Link 02/2020
1	ProdrugsIBA 02/2020
1	Oxidoreductases (Dehydrogenase)IBA 01/2019
1	SolutionsIBA 01/2018
1	quinolineIBA 01/2017
1	pyrrolidineIBA 01/2017
1	PiperazineIBA 01/2017
1	Estrogens (Estrogen)FDA Link 01/2016
1	Bile Acids and Salts (Bile Acids)IBA 02/2010
1	BilirubinIBA 02/2010
1	UGT1A3 UDP-glucuronosyltransferaseIBA 01/2010
1	EnzymesIBA 01/2010
1	AcidsIBA 01/2010

Therapy/Procedure

1	Drug Therapy (Chemotherapy) 10/2021
1	Therapeutics 07/2021